Sunday, February 23, 2020

Correcting Sickle Cell Disease using Stem Cells Essay

Correcting Sickle Cell Disease using Stem Cells - Essay Example The pattern of inheritance of sickle cell anemia is autosomal recessive. That means the symptoms will only possibly manifest if both parents are carrier of hemoglobin A. However, at present, the only available long term treatment for the disease is bone marrow transplant, which is prone to rejection and subsequent immune system reaction. The goals of other treatments, blood transfusion and pain medicines, are only for short-term relief of symptoms (Zieve and Chen, 2011). Recently, however, researchers from Johns Hopkins have found another plausible long term treatment for sickle cell anemia. By inserting the correct hemoglobin A gene to pluripotent bone marrow cells and removing the defective hemoglobin S, the patient can be able to produce RBCs that have the correct type of gene (Science Daily, 2011). Despite this new breakthrough in treatment, this does not prevent inheritance of the disease, because the gene to be transferred to an offspring is contained in sex cells, and not the bone marrow cells that are to be fixed using the new technology recently

Friday, February 7, 2020

Brand Management Term Paper Example | Topics and Well Written Essays - 2750 words

Brand Management - Term Paper Example ..9 Brand Positioning†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦10 Brand Value†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.11 Current Scenario†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..12 Conclusion & Recommendations†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦13 References†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.14 Introduction A Brand is the identity of a particular product or service, which distinguishes it from other products. The concept of branding has gained a lot of importance with the passage of time and nowadays branding has become an essential part of marketing for many companies. Nowadays, everything from a product to a person is a brand (Parameswaran, 2006). In this report, I will discuss the effectiveness of Nokia as a brand and evaluate it on various criteria that form the basis of brand management. Brand Management: Brand management understands what a ‘brand’ actually is and an approach to managing it in a way that it creates value for a company (Miller & Muir, 2004). A brand is the differentiating factor between two products which makes it special and gives it a competitive edge. A brand put forwards a promise which defines what the product has to offer to its customers. Marketers cr eate a proper image of the brand through visual images, logos, etc so that a customer can identify with it. Hence, brand management is a comprehensive process starting from understanding the brand to maintaining its image. Brand management can be simplified into 3 steps: First step is to create a promise i.e. understanding the brand and what it has to offer and defining it to the customer. Next is to make that promise which is how the image of the brand is created to register in the minds of the customers. Last is to keep the promise i.e. no brand can only survive on its name. A brand survives on what it offers to its customers and more. So brand management is also about living the promise of the brand till it exists. There are various ways to evaluate the effectiveness of a brand. The most important criteria are: Brand Image: A brand has a personality and a promise and the impression or image of that personality in the mind of a consumers’ mind of a brand’s character is known as brand image. Brand image is the overall impression of a brand that a consumer acquires from various sources. For example while purchasing a car Nissan would be associated with style, while Toyota is associated with reliability. Brand image is based on the fact that customer’s buying decision is associated with the image of the product and the customer is purchasing that set of beliefs (the image) that he has about the product. So a brand image should be positive and distinctive. Various promotional tools can be used to strengthen bran image like advertising, packaging etc. Brand Positioning: Positioning refers to how a product appears in the eyes of the target market as compared to other products